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The chronic total occlusion market size is projected to reach US$ 42.21 billion by 2031 from US$ 24.46 billion in 2024. The market is expected to register a CAGR of 8.2% during 2024–2031. Technological advancements in CTO devices are likely to bring new market trends during the forecast period.
Chronic Total Occlusion Market Analysis
The rising geriatric population is a key driver for the chronic total occlusion (CTO) market. As the world population grows older, cardiovascular diseases become more common. According to the US Census Bureau, the number of Americans aged 65 and above is expected to increase from 58 million in 2022 to 82 million by 2050, which is a 47% increase. The percentage of the population aged 65 and older is expected to increase from 17% to 23% by 2050. According to Statistics Canada, in 2022, around one in five Canadians (18.8% of the population; 7,329,910 people) were at least 65 years of age.
Older adults, particularly those over 60 years of age, are at higher risk of cardiovascular diseases due to age-related changes in the cardiovascular system, such as decreased blood vessel elasticity and arterial plaque. The growing elderly population worldwide is driving the need for efficient and minimally invasive treatments, such as percutaneous coronary intervention (PCI) for chronic total occlusion (CTO). Older adults often struggle to adjust to traditional surgical methods, which is why there is a rising preference for minimally invasive procedures that promote faster recovery and reduce risk. This is a phenomenon that can be seen in countries with high aging populations, such as the US, Japan, and European nations.
Market players such as Boston Scientific, Abbott Laboratories, and Medtronic are also more inclined to develop sophisticated CTO devices specifically designed for the aging population. These devices make treatments available, effective, and safe for this vulnerable group.
Chronic Total Occlusion Market Overview
The chronic total occlusion market is rapidly expanding due to the increasing aging population and the rising prevalence of cardiovascular diseases. Prominent players operating in the market are focusing on innovation and collaboration for enhanced product availability. However, the high cost of occlusion devices hinders the chronic total occlusion market growth.
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Chronic Total Occlusion Market: Strategic Insights
Market Size Value in US$ 280.7 Million in 2017 Market Size Value by US$ 516.1 Million by 2025 Growth rate CAGR of 8.1% from 2018-2025 Forecast Period 2018-2025 Base Year 2018
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Chronic Total Occlusion Market: Strategic Insights
| Market Size Value in | US$ 280.7 Million in 2017 |
| Market Size Value by | US$ 516.1 Million by 2025 |
| Growth rate | CAGR of 8.1% from 2018-2025 |
| Forecast Period | 2018-2025 |
| Base Year | 2018 |
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Chronic Total Occlusion Market Drivers and Opportunities
Rising Prevalence of Cardiovascular Diseases
The growing prevalence of cardiovascular diseases (CVDs) such as coronary heart diseases, sudden cardiac arrest, congenital heart diseases, heart failure, pulmonary hypertension, and pulmonary artery pressure (PA) is encouraging cardiovascular interventions. As the number of CVD patients continues to grow, so does the demand for advanced treatments for complex coronary conditions such as CTO. This increasing burden of disease has led to greater adoption of percutaneous coronary intervention (PCI) procedures for treating CTO, particularly in aging populations. According to the World Health Organization (WHO), ~30 million people experience a stroke each year. Moreover, the American Heart Association states more than 130 million people in the US, i.e., 45.1% of the population, are projected to have a type of CVD by 2035.
The European Society of Cardiology reported that atrial fibrillation is the most common arrhythmia, and it accounts for 0.28–2.6% of healthcare spending in European countries. It also mentioned that patients suffering from atrial fibrillation are at a five-time greater risk of getting a stroke, and 20–30% of total stroke cases in Europe are caused due to atrial fibrillation. As per a study conducted by the European Society of Cardiology in 2016, ~7.6 million people aged 65 and above had atrial fibrillation in the EU, and the number is estimated to increase by 89% to reach ~14.4 million by 2060. The prevalence of atrial fibrillation is estimated to reach 9.5% by 2060 from 7.8% in 2016. As per the report “Beyond the Burden: The Impact of Atrial Fibrillation in Asia Pacific,” by Biosense Webster, published in 2019, more than 16 million people in Asia Pacific suffer from atrial fibrillation, and the number is expected to reach ~72 million by 2050. The report also suggests that the middle-aged and elderly population is at a greater risk of developing this condition.
The WHO estimates 17.9 million lives are lost due to CVDs every year, i.e., 32% of the total deaths reported globally. A few of the primary risk factors of CVDs include family history, ethnicity, and age; other risk factors include tobacco consumption, hypertension, obesity, high cholesterol, physical inactivity, diabetes, unhealthy diets, and alcohol consumption. As CVD incidence continues to rise, the demand for CTO treatments is expected to expand, driving significant growth in the CTO market.
Strategic Initiatives by Market Players
Companies operating in the CTO market constantly focus on strategic developments such as product approvals, collaborations, funding, agreements, and new product launches, which help them improve their sales, increase their geographic reach, and reinforce their capacities to cater to a greater than existing customer base. A few strategic initiatives by key players operating in the CTO market are mentioned below.
- In February 2022, Teleflex Incorporated announced that the U.S. Food and Drug Administration (FDA) granted expanded indications for its specialty catheters and coronary guidewires, specifically for use in chronic total occlusion percutaneous coronary interventions (CTO PCI).
- In June 2024, MicroPort RotaPace’s Intravascular Piezoelectric Guidewire System gained NMPA approval for entry into the special review procedures for innovative medical devices. This system was co-developed by a team led by Academician Junbo Ge from Zhongshan Hospital, Fudan University.
- In February 2024, BIOTRONIK introduced the Micro Rx catheter, a novel rapid exchange microcatheter developed to easily enhance guidewire support during PCI. The Micro Rx catheter is the fourth IMDS product that BIOTRONIK has introduced to the US market, contributing to a strong portfolio of devices, which includes the NHancer Rx, TrapIT, and ReCross catheters.
- In October 2022, the FDA-approved NovaCross line of microcatheters (NovaCross BTK for below-the-knee treatment, NovaCross Xtreme for chronic total occlusion treatment, and NovaCross CTO for chronic total occlusion treatment) was among the assets that Microbot Medical Inc. purchased from Nitiloop Ltd. The NovaCross devices are designed to make it easier to implant conventional and steerable guidewires intraluminally beyond stenotic lesions, including chronic complete occlusions, prior to percutaneous transluminal coronary angioplasty or stent intervention.
- In April 2022, the FDA approved Transit Scientific's XO Cross Support Catheter Platform for coronary usage. The platform is intended to facilitate wire exchanges, guide and maintain a guidewire during access to the peripheral or coronary arteries, and serve as a conduit for the administration of diagnostic contrast agents or saline solutions.
- In February 2022, the FDA approved an additional indication for Teleflex Incorporated's specialized catheters and coronary guidewires to be used in crossing chronic complete occlusion (CTO) during percutaneous coronary intervention (PCI).
- In September 2023, Avinger, Inc. announced the full commercial launch of its Tigereye ST next-generation image-guided CTO crossing system. With the initiation of a full commercial launch, all current and prospective accounts can now order the Tigereye ST device.
Therefore, product launches, approvals, and collaborations are expected to create ample opportunities for the growth of the chronic complete occlusion (CTO) market in the coming years.
Chronic Total Occlusion Market Report Segmentation Analysis
Key segments that contributed to the derivation of the chronic total occlusion market analysis are equipment and end user.
- Based on equipment, the chronic total occlusion market is segmented into guide wires, micro catheters, crossing devices, re-entry devices, and others. The guide wires segment held the largest share of the market in 2024.
- In terms of end user, the chronic total occlusion market is categorized into hospitals, ambulatory care centers, and others. The hospitals segment dominated the market in 2024.
Chronic Total Occlusion Market Share Analysis by Geography
The geographic scope of the chronic total occlusion market report mainly focuses on five regions: North America, Asia Pacific, Europe, South & Central America, and the Middle East & Africa. In terms of revenue, North America dominated the market in 2024. It is expected to continue its dominance in the global market during the forecast period. The US is the largest market for chronic total occlusion in the world. The US chronic total occlusion market is growing with the rising incidence of CVD, especially Coronary Artery Disease (CAD), in the aging population. The American Heart Association’s (AHA) 2023 Heart Disease and Stroke Statistics Update mentions that approximately 18.2 million adults in the country had CAD. The adoption of minimally invasive methods, including percutaneous coronary intervention (PCI), and the development of sophisticated CTO-specific devices are the major driving forces for market growth. Global leaders such as Medtronic, Boston Scientific, Abbott Laboratories, and Philips Healthcare dominate the US market with their innovative devices and technologies for CTO procedures. The strong healthcare infrastructure, reimbursement policies, and emphasis on enhancing patient outcomes fuel market growth. The growing number of specialized centers and well-trained cardiologists favor the application of CTO procedures. As per the Division of Occupational Employment and Wage Statistics, there were 15,190 employed cardiologists in the US as of 2023. In addition, growing consciousness about cardiovascular health and detection of CTO at an early stage fuel the demand for these interventions.
Chronic Total Occlusion Market Report Scope
Chronic Total Occlusion Market News and Recent Developments
The chronic total occlusion market is evaluated by gathering qualitative and quantitative data post primary and secondary research, which includes important corporate publications, association data, and databases. Below are a few of the key developments witnessed in the chronic total occlusion market:
- Asahi Intecc Co., Ltd. announced that it has signed an agreement to establish a joint venture company with ELDORET HOSPITAL LTD to operate a new hospital specializing in cardiovascular diagnostics and treatments. (Source: Asahi Intecc Co., Ltd., Press Release, October 2023)
- BD (Becton, Dickinson and Company) announced the launch and 510(k) clearance from the FDA of the Crosser iQ CTO recanalization system, which is designed to cross peripheral artery chronic total occlusions (CTOs) intraluminally. (Source: BD, Press Release, January 2022)
Chronic Total Occlusion Market Report Coverage and Deliverables
The "Chronic Total Occlusion Market Size and Forecast (2021–2031)" report provides a detailed analysis of the market covering below areas:
- Chronic total occlusion market size and forecast at global, regional, and country levels for all the key market segments covered under the scope
- Chronic total occlusion market trends, as well as market dynamics such as drivers, restraints, and key opportunities
- Detailed PEST and SWOT analysis
- Chronic total occlusion market analysis covering key market trends, global and regional framework, major players, regulations, and recent market developments
- Industry landscape and competition analysis covering market concentration, heat map analysis, prominent players, and recent developments for the chronic total occlusion market
- Detailed company profiles
Report Coverage
Revenue forecast, Company Analysis, Industry landscape, Growth factors, and Trends
Segment Covered
Equipment ; End User and Geography
Regional Scope
North America, Europe, Asia Pacific, Middle East & Africa, South & Central America
Country Scope
US, Canada, Mexico, UK, Germany, Spain, Italy, France, India, China, Japan, South Korea, Australia, UAE, Saudi Arabia, South Africa, Brazil, Argentina
Frequently Asked Questions
North America dominated the market in 2024.
An increasing aging population and the rising prevalence of cardiovascular diseases are among the most significant factors fueling the market growth.
Technological advancements in CTO devices are likely to emerge as a new trend in the market in the coming years.
Asahi Intecc Co Ltd, Cordis Corp, Integer Holdings Corp, Boston Scientific Corp, Becton Dickinson and Co, SoundBite Medical Solutions, Medtronic Plc, Terumo Corp, Abbott, and Koninklijke Philips NV are among the key players operating in the market.
The chronic total occlusion market value is expected to reach US$ 42.21 billion by 2031.
The market is expected to register a CAGR of 8.2% during 2024–2031.
The List of Companies - Chronic Total Occlusion Market
- Asahi Intecc Co Ltd
- Cordis Corp
- Integer Holdings Corp
- Boston Scientific Corp
- Becton Dickinson and Co
- SoundBite Medical Solutions
- Medtronic Plc
- Terumo Corp
- Abbott
- Koninklijke Philips NV
The Insight Partners performs research in 4 major stages: Data Collection & Secondary Research, Primary Research, Data Analysis and Data Triangulation & Final Review.
- Data Collection and Secondary Research:
As a market research and consulting firm operating from a decade, we have published many reports and advised several clients across the globe. First step for any study will start with an assessment of currently available data and insights from existing reports. Further, historical and current market information is collected from Investor Presentations, Annual Reports, SEC Filings, etc., and other information related to company’s performance and market positioning are gathered from Paid Databases (Factiva, Hoovers, and Reuters) and various other publications available in public domain.
Several associations trade associates, technical forums, institutes, societies and organizations are accessed to gain technical as well as market related insights through their publications such as research papers, blogs and press releases related to the studies are referred to get cues about the market. Further, white papers, journals, magazines, and other news articles published in the last 3 years are scrutinized and analyzed to understand the current market trends.
- Primary Research:
The primarily interview analysis comprise of data obtained from industry participants interview and answers to survey questions gathered by in-house primary team.
For primary research, interviews are conducted with industry experts/CEOs/Marketing Managers/Sales Managers/VPs/Subject Matter Experts from both demand and supply side to get a 360-degree view of the market. The primary team conducts several interviews based on the complexity of the markets to understand the various market trends and dynamics which makes research more credible and precise.
A typical research interview fulfils the following functions:
- Provides first-hand information on the market size, market trends, growth trends, competitive landscape, and outlook
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- Develops the analysis team’s expertise and market understanding
Primary research involves email interactions and telephone interviews for each market, category, segment, and sub-segment across geographies. The participants who typically take part in such a process include, but are not limited to:
- Industry participants: VPs, business development managers, market intelligence managers and national sales managers
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Below is the breakup of our primary respondents by company, designation, and region:
Once we receive the confirmation from primary research sources or primary respondents, we finalize the base year market estimation and forecast the data as per the macroeconomic and microeconomic factors assessed during data collection.
- Data Analysis:
Once data is validated through both secondary as well as primary respondents, we finalize the market estimations by hypothesis formulation and factor analysis at regional and country level.
- 3.1 Macro-Economic Factor Analysis:
We analyse macroeconomic indicators such the gross domestic product (GDP), increase in the demand for goods and services across industries, technological advancement, regional economic growth, governmental policies, the influence of COVID-19, PEST analysis, and other aspects. This analysis aids in setting benchmarks for various nations/regions and approximating market splits. Additionally, the general trend of the aforementioned components aid in determining the market's development possibilities.
- 3.2 Country Level Data:
Various factors that are especially aligned to the country are taken into account to determine the market size for a certain area and country, including the presence of vendors, such as headquarters and offices, the country's GDP, demand patterns, and industry growth. To comprehend the market dynamics for the nation, a number of growth variables, inhibitors, application areas, and current market trends are researched. The aforementioned elements aid in determining the country's overall market's growth potential.
- 3.3 Company Profile:
The “Table of Contents” is formulated by listing and analyzing more than 25 - 30 companies operating in the market ecosystem across geographies. However, we profile only 10 companies as a standard practice in our syndicate reports. These 10 companies comprise leading, emerging, and regional players. Nonetheless, our analysis is not restricted to the 10 listed companies, we also analyze other companies present in the market to develop a holistic view and understand the prevailing trends. The “Company Profiles” section in the report covers key facts, business description, products & services, financial information, SWOT analysis, and key developments. The financial information presented is extracted from the annual reports and official documents of the publicly listed companies. Upon collecting the information for the sections of respective companies, we verify them via various primary sources and then compile the data in respective company profiles. The company level information helps us in deriving the base number as well as in forecasting the market size.
- 3.4 Developing Base Number:
Aggregation of sales statistics (2020-2022) and macro-economic factor, and other secondary and primary research insights are utilized to arrive at base number and related market shares for 2022. The data gaps are identified in this step and relevant market data is analyzed, collected from paid primary interviews or databases. On finalizing the base year market size, forecasts are developed on the basis of macro-economic, industry and market growth factors and company level analysis.
- Data Triangulation and Final Review:
The market findings and base year market size calculations are validated from supply as well as demand side. Demand side validations are based on macro-economic factor analysis and benchmarks for respective regions and countries. In case of supply side validations, revenues of major companies are estimated (in case not available) based on industry benchmark, approximate number of employees, product portfolio, and primary interviews revenues are gathered. Further revenue from target product/service segment is assessed to avoid overshooting of market statistics. In case of heavy deviations between supply and demand side values, all thes steps are repeated to achieve synchronization.
We follow an iterative model, wherein we share our research findings with Subject Matter Experts (SME’s) and Key Opinion Leaders (KOLs) until consensus view of the market is not formulated – this model negates any drastic deviation in the opinions of experts. Only validated and universally acceptable research findings are quoted in our reports.
We have important check points that we use to validate our research findings – which we call – data triangulation, where we validate the information, we generate from secondary sources with primary interviews and then we re-validate with our internal data bases and Subject matter experts. This comprehensive model enables us to deliver high quality, reliable data in shortest possible time.
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