Organ Preservation Solution Market is expected to reach US$ 512.62 Million by 2031

University of Wisconsin Solution Held Larger Share in Organ Preservation Solution Market in 2023

According to our new research study on "Organ Preservation Solution Market Forecast to 2031 – Global Analysis – by Product, Organ Type, Application, and End User," the market is expected to grow from US$ 274.41 million in 2023 to US$ 512.62 million by 2031; it is anticipated to record a CAGR of 8.2% from 2023 to 2031. The report emphasizes trends prevalent in the global market, along with drivers and deterrents affecting its growth. The increasing prevalence of chronic diseases and the rising need for organ transplantation are among the prominent factors driving the organ preservation solution market growth. However, the expensive organ transplant surgeries and limited organ availability are hampering the growth of the market. The shift towards machine perfusion technique is expected to bring new organ preservation solution market trends in the coming years.

Increasing Rising Need for Organ Transplantation Propels Organ Preservation Solution Market Growth

Transplantation surgeries are becoming more common worldwide. In 2023, the United Network for Organ Sharing recorded a count of more than 46,000 organ transplants in the US, marking an increase of over 8.7% from 2022. Additionally, the country crossed the mark of 27,000 kidney transplants for the first time in its history. The Council of Europe reported that an average of 39,000 patients received an organ transplant, while 48,000 new patients (nearly 5 patients per hour) were added to waiting lists across its member states in 2022. Patients who are on the organ waiting list typically suffer from end-stage organ disease, which significantly affects their quality of life, and this may indicate that they are nearing the end of their life. The rising number of individuals with end-stage organ failure triggers the need for timely organ transplantation. Due to advancements in transplantation techniques, more such people are now eligible for organ transplants. Organ preservation solutions are used to maintain the viability and function of organs for a certain period, allowing for their transport and subsequent transplantation into a recipient. The success of organ transplantation is primarily determined by organ preservation, surgery, immunotherapy, and post-operative care. Thus, a rising demand for organ transplantation drives the organ preservation solution market toward growth.

Organ Preservation Solution Market, by Region, 2023 (%)

The organ preservation solution market analysis has been carried out by considering the following segments: product, type, application, and end user. Based on product, the organ preservation solution market is segmented into University of Wisconsin Solution, Custodiol HTK, Perfadex, Hypothermosol, and Others. The University of Wisconsin Solution segment held the largest organ preservation solution market share in 2023. The UW solution is the most commonly used cold storage solution, which has been shown to have increased early pancreas graft function and decreased the incidence of preservation pancreatitis. As mentioned in an article published by the Experimental and Clinical Transplantation in June 2021, the UW solution is a gold standard solution widely used to preserve abdominal organs such as the pancreas due to its greater effectiveness in cold storage. In addition, UW-gluconate, a modified version, is used in experimental perfusion machines.

By organ type, the organ preservation solutions market is segmented into kidneys, liver, lungs, heart, and others. The kidneys segment held the largest market share in 2023. According to the Centers for Disease Control and Prevention (CDC) report published in 2021, more than 15% (1 in 7 or ~ 37 million) people in the US suffer from chronic kidney disease each year, with nearly 786,000 suffering from end-stage renal disease (ESRD). Various awareness campaigns are conducted to promote the benefits of kidney transplantation. For instance, in September 2022, the University Health Network's (UHN) Ajmera Transplant Centre announced the launch of a new campaign—Great Actions Leave a Mark—which showcased the stories and scars of 39 living organ donors and transplant recipients across Canada.

By application, the market is segmented into static cold storage, hypothermic machine perfusion, normothermic machine perfusion, and others. The static cold storage segment held the largest organ preservation solution market share in 2023. Static cold storage (SCS) is a recognized method in which the kidney is kept on ice following removal from the donor, and it is subsequently withdrawn from the ice box at the time of implantation. The preservation solution for the cold storage of transplanted kidneys is an ongoing topic of research. A study published in May 2020 in the American Journal of Transplantation assessed the effects of 5 preservation solutions for static cold storage on kidney transplant outcomes using data from the French national transplant registry maintained from 2010 to 2014. The article stated that the number of organs transplanted after undergoing static cold storage remains high, making up 58% of kidney transplants from donors after brain death (DBD) in France in 2018.

Based on end user, the organ preservation solutions market is segmented into organ transplant centers, hospitals, and specialty clinics. The organ transplant centers segment dominated the market in 2023. Transplant centers are healthcare facilities that are supervised and equipped to perform complex organ transplantation procedures; some of them also have a blood or marrow transplant program. Transplant centers are members of the Organ Procurement and Transplant Network (OPTN) and must meet requirements stated by the government. The US has more than 250 transplant centers, and 4 of these are functional in the service area covered by the Donor Alliance, a nonprofit organ procurement organization. All transplantation centers are connected with a parent hospital, hospital system, or university that compete with each other for organ procurement.

The geographic scope of organ preservation solution market report entails North America (the US, Canada, and Mexico), Europe (Spain, the UK, Germany, France, Italy, and Rest of Europe), Asia Pacific (South Korea, China, India, Japan, Australia, and Rest of Asia Pacific), the Middle East & Africa (South Africa, Saudi Arabia, the UAE, and Rest of the Middle East & Africa), and South & Central America (Brazil, Argentina, and Rest of South & Central America). In terms of revenue, North America accounted for the largest market share in 2023. In 2021, ~135,000 Americans were newly diagnosed with kidney failure. Also, 9 out of 10 people affected by kidney disease are unaware they have it, and 1 in 3 people with severely reduced kidney function are also unaware they have kidney disease. As per the same source, more than 250,000 Americans have undergone kidney transplants, and there are over 93,000 Americans on the kidney transplant waiting list. Therefore, factors such as the increasing adoption of technologically advanced products and solutions, and the surging number of organ transplants contribute notably to the expansion of organ preservation solution market size.

Competitive Landscape

Waters Medical Systems LLC, XVIVO Perfusion, TransMedics, OrganOx Limited, Paragonix Technologies, Inc, Dr. Franz Koehler Chemie GmbH, Accord Healthcare, ST CENTURY MEDICINE, Shanghai Genext Pharmaceutical Technology, and Bridge to Life Ltd are among the leading companies profiled in the organ preservation solution market report. The companies implement both organic (such as product launches, expansion, and product approvals) and inorganic (such as collaborations and partnerships) strategies to stay competitive in the market. 

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